The man allegedly assaulted a grocery store employee on Wednesday after he was asked to follow laws about wearing face coverings to slow the spread of the coronavirus, the CBC said, citing Ontario police.
The man refused, according to an employee at the store in Minden, about 200km north of Toronto, and fled after the incident.
Police were called but did not stop the suspect's car "in the interest of public safely", they said. Instead, they used his license plate to find his house.
Two officers were involved in the shooting, which was also confirmed by an independent investigation.
The man died shortly after being transported to a hospital, according to a statement from Ontario's Special Investigations Unit (SIU).
The man's identity is still unknown.
